Preparation of Compounds of Potential Physiological Activity: Derivatives of Benzilic, Substituted Acetic and Substituted Glycolic Acids and Substituted Butanones

Author

Thomas Alexander Magee, University of Tennessee - Knoxville

Date of Award

12-1957

Degree Type

Dissertation

Degree Name

Doctor of Philosophy

Major

Chemistry

Major Professor

C.A. Buehler & H.A. Smith

Committee Members

W.E. Deeds, David King, & David A. Shirley

Abstract

The continuing search of chemists, physiologists and medical researchers for natural and synthetic compounds which will alleviate or cure the illnesses of mankind constitutes a fascinating episode in the history of scientific endeavor. One chapter of this history is necessarily concerned with efforts to synthesize better, more useful antispasmodics. To present a comprehensive critical review of these efforts would require an extensive treatise and will not be attempted here. Several reviews are available which cover the literature to around 1950. The present survey will be a brief resume of the more pertinent material to the present time. It is hoped that this resume will afford to the reader some background in and appreciation of the field, together with an understanding of the synthetic approaches involved.

Recommended Citation

Magee, Thomas Alexander, "Preparation of Compounds of Potential Physiological Activity: Derivatives of Benzilic, Substituted Acetic and Substituted Glycolic Acids and Substituted Butanones. " PhD diss., University of Tennessee, 1957.
https://trace.tennessee.edu/utk_graddiss/3258