Masters Theses
Date of Award
8-1994
Degree Type
Thesis
Degree Name
Master of Science
Major
Nuclear Engineering
Major Professor
Peter G. Groer
Committee Members
Laurence Miller, Michael Fry
Abstract
A Bayesian statistical method was developed to estimate the parameters for the following survival model characterized by the probability density f(t,d)=αλα&iotaα-1&e&rho&betade-(λ&iota)αe&rho&betad Computer programs were developed in "Mathematica" (10) to calculate the posterior densities for the model parameters α, &beta, λ, and &rho. The data used in the analyses came from BALB/c female mice exposed to 137Cs gamma radiation (5,6). The doses ranged from 0 to 2 Gy with dose rates from 0.083 Gy/day to 0.4 Gy/min (5,6). The data were generated at the Biology division of Oak Ridge National Lab (ORNL) and supplied by ORNL and the National Radiobiology Archives. The parameter &rho describes the effect of dose-rate on the induction of cancer in mice. The derived posterior density for p describes the remaining uncertainty about the parameter after updating. This thesis describes the first direct estimation of a dose-rate effectiveness factor (DREF) using the techniques of Bayesian parameter estimation and gives the first quantitative description of the uncertainty of this factor in terms of a probability density.
Recommended Citation
Auerbach, Patrick Evan, "AIAW large college/division I basketball's impact on women's intercollegiate athletics, 1971-1982. " Master's Thesis, University of Tennessee, 1994.
https://trace.tennessee.edu/utk_gradthes/11428