Synthesis of isobutyl and pentyl C-4 substituted derivatives of naturally occurring (+)-calanolide A and (-)-calanolide B

Author

Michael Sean Gaines

Date of Award

5-1997

Degree Type

Thesis

Degree Name

Master of Science

Major

Chemistry

Major Professor

David C. Baker

Committee Members

Ron Magid, John Bartmess

Abstract

This research develops (+)-calanolide A and (-)-calanolide B derivatives that could potentially be used as drugs to inhibit HIV reverse transcriptase. The main emphasis of this research is the synthesis of isobutyl and pentyl C-4 substituted derivatives.

Recommended Citation

Gaines, Michael Sean, "Synthesis of isobutyl and pentyl C-4 substituted derivatives of naturally occurring (+)-calanolide A and (-)-calanolide B. " Master's Thesis, University of Tennessee, 1997.
https://trace.tennessee.edu/utk_gradthes/10524