Halogenations using sodium halides with sodium perborate in acetic acid and allylboration of β-ketoacids

Author

Kaihong Yang

Date of Award

5-2000

Degree Type

Dissertation

Degree Name

Doctor of Philosophy

Major

Chemistry

Major Professor

George W. Kabalka

Abstract

Sodium perborate is an inexpensive, stable and easy to handle reagentIn the course of a study focused on halogenation reactions, we developed a new bromination procedure using NaBr/NaBO₃ in HOAC. It provides a highly efficient, economical, and environmentally friendly method for brominating organic molecules.

In a study of allylboration reactions, we found that β-ketoacids can be easily allylboronated by β-diisopropoxyborane to yield tertiary β-hydroxyacids in good yields.

Recommended Citation

Yang, Kaihong, "Halogenations using sodium halides with sodium perborate in acetic acid and allylboration of β-ketoacids. " PhD diss., University of Tennessee, 2000.
https://trace.tennessee.edu/utk_graddiss/8452