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  5. Production of Protactinium-229 via Deuteron Irradiation of Thorium-232
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Production of Protactinium-229 via Deuteron Irradiation of Thorium-232

Date Issued
December 1, 2021
Author(s)
Burahmah, Naser  
Advisor(s)
Lawrence H. Heilbronn
Additional Advisor(s)
Howard L. Hall
Jason P. Hayward
Robert M. Counce
Permanent URI
https://trace.tennessee.edu/handle/20.500.14382/28313
Abstract

225Ac [Actinium-225] is a promising radionuclide for targeted alpha therapy of cancer. 229Pa can lead to the production of 229Th [Thorium-229] and 225Ac [Actinium-225]. Deuteron bombardment on natural thorium targets has been investigated to measure cross sections of protactinium isotopes. In this work, 229Pa [Protactinium-229] excitation function was measured via deuteron energies up to 50 MeV [Mega electron volt] of thin thorium foils. The irradiation took place at Lawrence Berkeley National Laboratory’s (LBNL) 88-Inch Cyclotron. The target processing and analysis were performed at Oak Ridge National Laboratory (ORNL). The target consisted of 4 thin foils (~17 mg/cm2 [milligrams per square centimeter]) in a stacked-target configuration, and were irradiated with 1 μA [microampere] for approximately 11 continuous hours. Column chromatography techniques had been implemented to observe 229Pa due to its weak γ-rays [gamma-rays]. The primary motivation of this work is to quantify the production routes of 229Th. 232Th(d,5n)229Pa reaction cross sections are reported for the first time. The peak of the excitation function of 232Th(d,5n)229Pa at 121.9 ± 12.7 mb [millibarns] occurs at Ed = 35.2 MeV. The production cross sections of 232Th(d,xn)228,230,232,233Pa reactions, where x = 1,2,4, and 6, are also reported. Other measured cross sections are in excellent agreement with published data in the literature. The experimental cross sections were compared with transport code using Particle and Heavy Ion Transport code System (PHITS) and exhibited good agreement.

Subjects

Actinium-225

Protactinium-229

Isotope production

Monte Carlo simulatio...

Deuteron irradiation

Targeted Alpha Therap...

Disciplines
Nuclear
Nuclear Engineering
Degree
Doctor of Philosophy
Major
Nuclear Engineering
Embargo Date
December 15, 2023
File(s)
Thumbnail Image
Name

Dissertation_Final.docx

Size

4.91 MB

Format

Microsoft Word XML

Checksum (MD5)

777c0e18a5c35c9baf0b7e4f81623acf

Thumbnail Image
Name

auto_convert.pdf

Size

2.45 MB

Format

Adobe PDF

Checksum (MD5)

82fffaa805da184416492365ee854553


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