Source Publication (e.g., journal title)

Journal of Chromatographic Science

Document Type


Publication Date





A new method of analysis has been developed and validated for the determination of meloxicam in egg whites and yolks. Following a liquid extraction for the whites and a solid phase extraction for the yolks, samples were separated on an XBridge C18 column and quantified using ultraviolet detection at 360 nm. The mobile phase was a mixture of water with glacial acetic acid and aceto- nitrile, with a flow rate of 1 mL/min. The procedure produced a linear graph over the concentration range 5–1500 ng/mL with a lower limit of quantification of 5 ng/mL. Intra- and inter-assay variabil- ity was 10% or less for both the whites and yolks. The average recovery for whites was 96% and the average recovery in yolks was 97%.

Submission Type

Publisher's Version

Files over 3MB may be slow to open. For best results, right-click and select "save as..."