Separation of Optical Isomers by Solvent Extraction

The purpose of this research was to develop a solvent extraction method to resolve optical isomers. Earlier work²⁵ done in this laboratory has indicated that partial resolution had been obtained by using D(+)-diisopropyl tartrate and water as the immiscible solvent system. Further work done by the author indicates that this method can be used to partially resolve racemic modifications. Before this method is discussed in detail, a summary of the known methods of resolution should be presented.