Binding of aflatoxin B1 to dietary fiber components In vitro

Experiments were undertaken to define the binding of a chemical carcinogen, aflatoxin B₁, to dietary fiber preparations (neutral detergent fiber, acid detergent fiber, acetone fiber and lignin). Five product sources were used: wheat bran, corn bran, peanut hull, alfalfa meal and pear. The results of this study indicated dietary fiber from different plant sources has the ability to bind aflatoxin B₁ in a stable complex. Based on these findings the following conclusions were made. With regard to the main effects of product and fiber types, peanut hull was found to have the greatest aflatoxin B₁ binding ability of the products. Lignin possessed the greatest aflatoxin B₁ binding ability among the four fiber types. With regard to interaction of product and fiber type, peanut hull lignin had the greatest ability to bind aflatoxin B₁ and wheat bran NDF showed the least aflatoxin B₁ binding ability. Duncan's Multiple Range Test (α = 0.05) partitioned the treatment combinations into four groups with overlapping, while the Student-Newman-Keuls Test (α = 0.05) produced a more conservative division of three groups with overlapping